Break Free from Treatment-Resistant Depression.
If two or more oral antidepressants haven't worked, SPRAVATO® offers a new approach to reducing depression symptoms.
Living with Depression Even After Trying Multiple Treatments? You're Not Alone.
It can be incredibly disheartening when you've put your trust in medication, diligently taking oral antidepressants, yet still find yourself struggling with the weight of depression. This experience isn't uncommon, and it has a name: treatment-resistant depression. Simply put, it means that two or more different oral antidepressants, taken at adequate doses and for a sufficient duration, haven't provided the relief you need.
This can leave you feeling frustrated, hopeless, and wondering if there are any other options. You might even question if you'll ever truly feel better. It's important to know that these feelings are valid, and you're not alone in this journey.
Research offers some insight into this challenge. Studies suggest that after the third oral antidepressant, the likelihood of achieving remission can significantly decrease, dropping below 14%. If you've tried two or more oral antidepressants and are still experiencing persistent depressive symptoms, it may be a sign that your depression is treatment-resistant, and it might be time to explore a different kind of approach.
Introducing SPRAVATO®: A Different Approach to Depression Relief.
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The only FDA-approved nasal spray for adults (18+) with treatment-resistant depression.
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Clinically proven to reduce depressive symptoms when two or more oral antidepressants haven't worked.
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Offers a greater reduction in depressive symptoms at four weeks compared to placebo and an oral antidepressant.
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In a long-term study, continued SPRAVATO® treatment helped prevent the return of depressive symptoms.
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I’ve tried two or more oral antidepressants, and I am still experiencing depression. Do I have treatment-resistant depression?A study suggests that after the third oral antidepressant, remission rates dropped below 14%. If you’ve tried two or more oral antidepressants and are still experiencing depressive symptoms, you may have treatment-resistant depression, and it may be time for something different.
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Since my other oral antidepressants haven’t worked, what are the chances another oral antidepressant will work? Should I try something entirely different?Treatment-resistant depression is defined as not responding to two or more antidepressants of adequate dose and duration. If your doctor has diagnosed you with treatment-resistant depression, you may benefit from treatment with a different kind of medication.
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What can you tell me about the safety of SPRAVATO®?It is important to understand the potential side effects of any medication you consider taking. To help ensure safety, SPRAVATO® is available only through a restricted distribution program called the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) Program.
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How often are SPRAVATO® treatment sessions required?The number of SPRAVATO® treatment sessions the healthcare provider recommends depends on a variety of factors. In general, patients receive two doses of SPRAVATO® each week in separate sessions. After the first several weeks, the healthcare provider may reduce the number of sessions to one per week.
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How is SPRAVATO® nasal spray different than ketamine infusion?SPRAVATO® (esketamine) CIII nasal spray is a derivative of ketamine. SPRAVATO® is an FDA-approved nasal spray for treatment-resistant depression; it is also approved to treat depressive symptoms in adults with major depressive disorder with suicidal thoughts or actions. Ketamine has not been approved by the FDA to treat depression. Both SPRAVATO® and ketamine are Schedule III controlled substances under the US Controlled Substances Act.
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Is Spravato addictive?There is no evidence to suggest that SPRAVATO®, which is used carefully in appropriate doses within a supervised facility, leads to dependence (or addiction) to the substance. With that said, there are ties to ketamine that are used for recreational purposes and can be addictive when taken irresponsibly, so it is important to avoid ketamine use outside of a supervised facility.
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Could SPRAVATO® interact with any other medications I may be taking?Before starting SPRAVATO®, tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicines or alcohol may cause side effects. Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants or monoamine oxidase inhibitor (MAOI) medicine. If you use a nasally administered medication like a nasal steroid or decongestant spray, do not administer it within the hour before you will be taking SPRAVATO®.
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Is SPRAVATO® medication covered under my medical or pharmacy benefit?SPRAVATO® can fall under the medical or pharmacy benefit depending on your coverage, so it’s important to ask and relay this to your healthcare provider.
Ready to Explore if SPRAVATO® is Right for You?
Schedule a consultation today!